Parathyroid tumors and related disorders

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Dermatologic manifestations of parathyroid-related disorders.

Dermatologic manifestations of parathyroid-related disorders, although rare in sporadic cases, are not uncommon in familial syndromes. Patients with familial hyperparathyroidism have several types of skin lesions. In multiple endocrine neoplasia 1, patients commonly have angiofibromas (85%) and collagenomas (70%), lesions that show loss of one 11q13 allele, the molecular abnormality in multiple...

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Parathyroid disorders.

Disorders of the parathyroid glands most commonly present with abnormalities of serum calcium. Patients with primary hyperparathyroidism, the most common cause of hypercalcemia in outpatients, are often asymptomatic or may have bone disease, nephrolithiasis, or neuromuscular symptoms. Patients with chronic kidney disease may develop secondary hyperparathyroidism with resultant chronic kidney di...

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Parathyroid Disorders.

Parathyroid hormone (PTH) is a peptide hormone that is the primary regulator of calcium concentrations in the bloodstream. PTH is released in response to a variety of signals, most importantly in response to low serum calcium concentrations. As a true hormone, it travels through the bloodstream to target tissues, primarily in the bone and kidney, where it has a variety of effects that serve to ...

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Inflammatory infiltrates in parathyroid tumors

CONTEXT Inflammatory infiltrates are sometimes present in solid tumors and may be coupled to clinical behavior or etiology. Infectious viruses contribute to tumorigenesis in a significant fraction of human neoplasias. OBJECTIVE Characterize inflammatory infiltrates and possible viral transcription in primary hyperparathyroidism. DESIGN From the period 2007 to 2016, a total of 55 parathyroid...

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Neurological MaNifestatioNs of thyroid aNd Parathyroid disorders

609 IntroductIon Endocrine diseases have protean manifestations and present with a wide variety of symptoms pertaining to different bodily systems. This results, at times, in diagnostic delays and dilemmas; hence it is important for the clinician to be familiar with the neurological manifestations of endocrinopathies. Amongst various endocrinal disorders, the thyroid diseases are common and to ...

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ژورنال

عنوان ژورنال: Modern Pathology

سال: 2011

ISSN: 0893-3952,1530-0285

DOI: 10.1038/modpathol.2010.132